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Wood Michael W Targets and Emerging - limbobo.ru

Wood Michael W. Targets and Emerging Therapies for Schizophrenia

New and emerging directions in pharmaceutical research to better treat schizophrenia Although the dopamine hypothesis has been the cornerstone of schizophrenia therapeutics, it is clear that dopamine-based approaches do not treat all aspects of the disease. Moreover, many schizophrenia patients fail to respond to current antipsychotics. Integrating chemistry, biology, and pharmacology, this book explores emerging directions in pharmaceutical research for drug targeting and discovery in order to find more effective treatments for schizophrenia, one of the most serious and widespread psychiatric diseases. Targets and Emerging Therapies for Schizophrenia presents the basics of schizophrenia, drug targets for the disease, and potential new drugs and therapeutics. It begins with a discussion of prevalence and etiology. Then, it describes therapies such as dopamine agonists and phosphodiesterase (PDE) inhibitors as well as growing research aimed at addressing untreated symptoms. Next, the authors discuss receptor modulators, inhibitors, and targeting strategies for drug discovery. Both the neurobiological and chemical aspects of all major pharmacological targets are examined. With contributions from an international team of pioneering pharmaceutical researchers, this book compiles the current knowledge in the field, setting the stage for new breakthroughs in the treatment of schizophrenia. Targets and Emerging Therapies for Schizophrenia: Provides a comprehensive resource for neuro-drug discovery and the development of molecular targets for schizophrenia treatment Draws from chemistry, biology, and pharmacology for more effective drug targeting and discovery Explores a wide range of receptors and molecular targets, including dopamine, PDEs, and neuropeptides With Targets and Emerging Therapies for Schizophrenia as their guide, drug discovery and development scientists have the information they need to advance their own research so that new, more effective treatments for schizophrenia will soon be a reality.

18013.38 RUR

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Shooting Airgun Target Paintball and BB Gun & Cone-shaped Black Pellet Trap W. 20 Pcs Paper Targets

Michael W. Austin Football and Philosophy

Michael W. Dong HPLC and UHPLC for Practicing Scientists

Evans Virginia, Dooley Jenny Grammar Targets 1. Student's Book. Учебник

Grammar Targets 1 gives students at Beginner level clear explanations and practice of English grammar. Key features: Clear simple explanations and examples; A variety of stimulating exercises; Lively illustrations; Revision units; Exploring grammar sections. Components: Grammar Targets 1 Student's Book; Grammar Targets 1 Key.

1169 RUR

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Michael E. Wood Newhall Shooting - A Tactical Analysis

As the son of a California Highway Patrolman who was a contemporary of the slain officers in the famed 1970 Newhall shooting,  Michael E. Wood  grew up hearing about the event and its influence on the CHP and law enforcement community. That experience led to his authoring  Newhall Shooting: A Tactical Analysis , arguably the most thoroughly researched and documented account of the shooting to date. He is a lifelong shooter and student of armed self-defense and a graduate of civilian self-defense training schools, including the Lethal Force Institute and The HALO Group. Wood is a military officer and pilot with 22 years of experience in operational environments, including combat operations, and is accustomed to analyzing events and deriving «lessons learned» for application in training and programs.

1168.41 RUR

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Fisher Investments Fisher Investments on Emerging Markets

The fifth installment of the Fisher Investments On series is a comprehensive guide to understanding and analyzing investment opportunities within emerging markets. Growing in relative importance in recent years, emerging markets offer dynamic and unique opportunities. Fisher Investments on Emerging Markets can benefit both new and seasoned investors, covering everything from regional basics to country-specific insights to practical investing tactics, including common pitfalls to avoid. This book begins with an overview of emerging markets, followed by a historical narrative of the major emerging market regions—with emphasis on the economic, political, and sentiment drivers that help shape the investing landscape. Discusses regional, and even country-specific, drivers. Examines the major regions, including Russia, China, Latin America, and Asia. Addresses the challenges unique to emerging and developing regions, and some common pitfalls to avoid. Delves into top-down investment methodology as well as individual security analysis. Outlines a five-step process to help differentiate firms in emerging markets—designed to help you identify ones with the greatest probability of outperforming Provides investment strategies for a variety of market environments Filled with in-depth insights and expert advice, Fisher Investments on Emerging Markets provides a framework for understanding emerging markets. With this book as your guide, you can quickly gain a global perspective on emerging markets and discover strategies to help achieve your investing goals.

2329.45 RUR

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Jean-Claude Sabonnadière Renewable Energy Technologies

This book deals with the emerging generation of renewable energy technologies, covering solar energy (photovoltaic, thermal and thermodynamic energy conversion), wind energy, marine energy, small hydropower, geothermal energy, biofuels, biogas and the use of wood as a substitute for fossil fuels.

18386.72 RUR

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Prakash S. Bisen Emerging Epidemics

A global perspective on the management and prevention of emerging and re-emerging diseases Emerging infectious diseases are newly identified or otherwise previously unknown infections that cause public health challenges. Re-emerging infectious diseases are due to both the reappearance of and an increase in the number of infections from a disease that is known, but which had formerly caused so few infections that it was no longer considered a public health problem. The factors that cause the emergence or re-emergence of a disease are diverse. This book takes a look at the world's emerging and re-emerging diseases. It covers the diagnosis, therapy, prevention, and control of a variety of individual diseases, and examines the social and behavioral issues that could contribute to epidemics. Each chapter focuses on an individual disease and provides scientific background and social history as well as the current basics of infection, epidemiology, and control. Emerging Epidemics: Management and Control offers five topics of coverage: FUNDAMENTALS Epidemics fundamentals Disasters and epidemics Biosafety RE-EMERGING EPIDEMICS Tuberculosis Plague NEWLY EMERGING EPIDEMICS Leptospirosis Dengue Japanese Encephalitis Chikungunya Fever West Nile Virus Chandipura Virus Encephalitis Kyasanur Forest Disease Hantavirus Human, Avian, and Swine Influenza Severe Acute Respiratory Syndrome Nipah Virus Paragonimiasis Melioidosis POTENTIAL EPIDEMICS Biowarfare and bioterrorism Food contamination and food terrorism Antimicrobial resistance VECTOR CONTROL METHODS Mosquito control Other disease vectors and their control Offering an integrated, worldwide overview of the complexity of the epidemiology of infections, Emerging Epidemics will be a valuable resource for students, physicians, and scientists working in veterinary, medical, and the pharmaceutical sciences.

17777.35 RUR

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Группа авторов Human Emerging and Re-emerging Infections

Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the “novel” nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.

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Targets - Wikipedia

Targets is a 1968 American crime thriller film directed, co-written and co-produced by Peter Bogdanovich, with cinematography by László Kovács.. In one of two parallel story lines that eventually converge during the film's climax, a seemingly wholesome and normal young man played by Tim O'Kelly suddenly goes on a killing spree. In the other, Boris Karloff, in his last straight dramatic role ...

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Michael Wood (historian) - Wikipedia

Michael David Wood (born 23 July 1948) is an English historian and broadcaster. He has presented numerous well-known television documentary series from the late 1970s to the present day. Wood has also written a number of books on English history, including In Search of the Dark Ages, The Domesday Quest, The Story of England, and In Search of Shakespeare.

How To Set Performance Targets That Work

How To Set Performance Targets That Work “Aim for the moon. If you miss, you may hit a star.” A famous quote by self-help business guru W. Clement Stone. It says a lot about why targets are important to every company and individual – and why it’s important to push yourself to aim high. In business terms, a target is a goal that the company is aiming to reach. But targets don’t just ...

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Woody's Targets are made of wood and have a built-in stake- no target stand needed. If you are unfamiliar with how to use a Woody, you just push it in and shoot it. Available in a variety of different styles. For use with rifle, pistol, rim fire, air gun. All calibers punch perfect holes. Product details . Color: Bottle Target. Product Dimensions: 1 x 1 x 1 inches Shipping Weight: 6.4 ounces ...

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Wooden skyscrapers: Has the revolution arrived? - CNN Style

Wooden skyscrapers -- sometimes dubbed "plyscrapers" -- were once the preserve of conceptual designers. But they are quickly becoming a reality. Find out why.

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Wood Target - Official The Forest Wiki

The wood target is a building intended for practicing your ranged weapon and throw skills, and it can be found the the utility section of the Survival Guide. The wood target is useful for practicing your aiming with the bow and arrows can be collected from the surface of the target after it has been used. The Wood Target is unique in that it doesn't take player weapon damage, with the ...

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Informationen zu Targets (Deutschland) inkl. Diskographie (CDs, LPs, ...), Biographie, Links, etc.

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Michael Woods – Wikipedia

Michael Woods ist der Name folgender Personen: . Michael Woods (Politiker) (* 1935), irischer Politiker Michael Woods (Schauspieler) (* 1957), US-amerikanischer Schauspieler Michael Woods (Fußballspieler, 1962) (* 1962), maltesischer Fußballspieler Michael Woods (Musiker), britischer DJ und Musikproduzent Michael Woods (Radsportler) (* 1986), kanadischer Radrennfahrer

Michael Woods (Politiker) – Wikipedia

Michael J. Woods (irisch Mícheál Ó hUadhaigh, * 8. Dezember 1935 im County Wicklow) ist ein irischer Politiker der Fianna Fáil und langjähriger Minister.. Biografie. Woods war nach der Promotion als Berater für Marketing und geschäftsführender Direktor von Unternehmen tätig. Seine politische Laufbahn begann er als Kandidat der Fianna Fáil 1977 mit der erstmaligen Wahl zum Mitglied ...

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Manchester - WOOD Restaurant Group

WOOD Manchester is Simon Wood’s flagship restaurant, situated in the heart of Manchester City Centre, on Jack Rosenthal Street in First Street. Since opening in September 2017, WOOD Manchester has achieved local and national recognition. The restaurant is recommended in the 2020 edition of the MICHELIN Guide – Great Britain & Ireland . Visitors to WOOD Manchester can enjoy menus created ...

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Botana Luis M. Therapeutic Targets. Modulation, Inhibition, and Activation

The Latest Applications For Cellmechanism Research in Drug Discovery Designed to connect research on cell mechanisms with the drug discovery process, Therapeutic Targets: Modulation, Inhibition, and Activation introduces readers to a range of new concepts and novel approaches to drug screening and therapeutic drug targeting to help inform future avenues of drug research. Highly topical, this accessible edited volume features chapters contributed by respected experts from around the globe. The book helps postgraduate students and professional scientists working in academia and industry understand the molecular mechanisms of pharmacology, current pharmacological knowledge, and future perspectives in drug discovery, focusing on important biochemical protein targets and drug targeting strategies for specific diseases. Examining the pharmacology of therapeutically undefined targets and their potential applications, it includes chapters on traditional therapeutic targets, including enzymes (phosphodiesterases and proteases), ion channels, and G protein-coupled receptors, as well as more recently identified avenues of exploration, such as lipids, nuclear receptors, gene promoters, and more. Since different diseases require different targeting techniques, the book also includes dedicated chapters on strategies for investigating Alzheimer's, diabetes, pain, and inflammation treatments. Concluding with a cross-sectional look at new approaches in drug screening, Therapeutic Targets is an invaluable resource for understanding where the next generation of drugs are likely to emerge.

15395.38 RUR

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Шкаф-пенал Clarberg Papyrus-wood Pap-w.05.35/LIGHT

Papyrus-wood пенал подвесной, цвет светлое дерево Pap-w.05.35/LIGHT,
Гарантия: 2 года

79692 RUR
Papyrus-wood Pap-w.05.35/LIGHT Clarberg

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Тумба под раковину Clarberg Papyrus-wood Pap-w.01.10/LIGHT

Papyrus-wood тумба под умывальник подвесная, цвет светлое дерево Pap-w.01.10/LIGHT,
Гарантия: 2 года

121316 RUR
Papyrus-wood Pap-w.01.10/LIGHT Clarberg

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Michael Wood Conquistadors

Susan M. Brookhart Learning Targets

In Learning Targets , Connie M. Moss and Susan M. Brookhart contend that improving student learning and achievement happens in the immediacy of an individual lesson–what they call «today's lesson»—or it doesn't happen at all. The key to making today's lesson meaningful? Learning targets. Written from students' point of view, a learning target describes a lesson-sized chunk of information and skills that students will come to know deeply. Each lesson's learning target connects to the next lesson's target, enabling students to master a coherent series of challenges that ultimately lead to important curricular standards. Drawing from the authors' extensive research and professional learning partnerships with classrooms, schools, and school districts, this practical book – Situates learning targets in a theory of action that students, teachers, principals, and central-office administrators can use to unify their efforts to raise student achievement and create a culture of evidence-based, results-oriented practice. – Provides strategies for designing learning targets that promote higher-order thinking and foster student goal setting, self-assessment, and self-regulation. – Explains how to design a strong performance of understanding, an activity that produces evidence of students' progress toward the learning target. – Shows how to use learning targets to guide summative assessment and grading. Learning Targets also includes reproducible planning forms, a classroom walk-through guide, a lesson-planning process guide, and guides to teacher and student self-assessment. What students are actually doing during today's lesson is both the source of and the yardstick for school improvement efforts. By applying the insights in this book to your own work, you can improve your teaching expertise and dramatically empower all students as stakeholders in their own learning.

2254.78 RUR

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Gordian Gaeta Opportunities in Emerging Markets. Investing in the Economies of Tomorrow

The practical guide to investing in emerging markets Though potentially risky, investing in emerging markets can offer extremely attractive returns. Opportunities in Emerging Markets offers practical advice for investors based on the real life experiences—both positive and negative—of practitioners, pioneer investors, and local heroes with experience in frontier markets. Exploring how every developing market has its own unique regional cultures and social structures that change the way investors invest, and must be understood in order to make wise investments, the book combines standard approaches to investing with the exigencies of frontier markets to create an invaluable framework for success. A collection of useful ideas that investors—institutions, general partners, limited partners, or shareholders—can draw upon when investing money in emerging markets, the book includes essential information on one of the most attractive opportunities for beating traditional markets and investments. If access, downside, and predictability can be managed, there's a great deal of money to be made in emerging markets, and this book shows how. Both investors and investment managers need to understand fundamental success factors, real framework conditions, and hidden pitfall and in Opportunities in Emerging Markets, author Gordian Gaeta analyses these intricacies in depth. Gives investors of all kinds the information they need to succeed in emerging markets Incorporates real life experiences—both good and bad—to help readers avoid common mistakes and maximize their returns Includes interviews with Mark Mobius, Jim Rogers, Marc Faber, and other leading names in the emerging markets sector For those traders brave enough to engage in high-risk/high-return investing, Opportunities in Emerging Markets is an excellent overview of the world's toughest frontier markets and how to conquer them. Featuring interviews with some of the top investors in the field, this is the definitive guide to the perils and pitfalls of investing in these highly volatile markets.

9333.36 RUR

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Edward D. Zanders Human Drug Targets

The identification of drug targets in a given disease has been central to pharmaceutical research from the latter half of the 20th century right up to the modern genomics era. Human Drug Targets provides an essential guide to one of the most important aspects of drug discovery – the identification of suitable protein and RNA targets prior to the creation of drug development candidates. The first part of the book consists of introductory chapters that provide the background to drug target discovery and highlight the way in which these targets have been organised into online databases. It also includes a user’s guide to the list of entries that forms the bulk of the book. Since this is not designed to be a compendium of drugs, the emphasis will be on the known (or speculated) biological role of the targets and not on the issues associated with pharmaceutical development. The objective is to provide just enough information to be informative and prompt further searches, while keeping the amount of text for each of the many entries to a minimum. Human Drug Targets will prove invaluable to those drug discovery professionals, in both industry and academia, who need to make some sense of the bewildering array of online information sources on current and potential human drug targets. As well as creating order out of a complex target landscape, the book will act as an ideas generator for potentially novel targets that might form the basis of future discovery projects.

12261.76 RUR

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Grammar Targets 3. Students Book. Учебник

Grammar Targets 3 gives students at Pre-lntermediate level clear explanations and practice of English grammar. .Key features: .•clear simple explanations and examples .•a variety of stimulating exercises .•lively illustrations .•revision units .•exploring grammar sections. .

1513 RUR

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Evans Virginia, Dooley Jenny Grammar Targets 2. Student's Book. Учебник

Grammar Targets 2 gives students at Elementary level clear explanations and practice of English grammar. Key features: - clear simple explanations and examples; - a variety of stimulating exercises; - lively illustrations; - revision units; - exploring grammar sections.

1536 RUR

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Evans Virginia, Dooley Jenny Grammar Targets 3. Student's Book. Учебник

Grammar Targets 3 gives students at Pre-lntermediate level clear explanations and practice of English grammar. Key features: - clear simple explanations and examples - a variety of stimulating exercises - lively illustrations - revision units - exploring grammar sections.

1376 RUR

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